Abstract: Experiments were carried out to study minimum bactericidal concentration(MBC) of 5 kinds of disinfectants(double fouthdiamine sait-iodine solution,compound aldehyde,chlorine-containing disinfectant;sodium hydroxide and potassium permanganate) against 5 kinds of pathogenic bacteria,and the above MBCs of disinfectants were 1:600-1:800,1:1000-1:2500,1:30000-1:40000,0.01%-0.03% and 0.0008%-0.004%,respectively.It emphatically evaluated the sterilized efficacy of each kind of disinfectant to salmonella at different temperatures.The results showed that following the increase of environmental temperature,the MBC of double fouthdiamine sait-iodine solution went up,but the MBC of compound aldehyde was down and the MBC of other three kinds of disinfectants did not change with environmental temperature.The highest salmonella concentrations killed by 5 kinds of MBC of disinfectants reached 106cfu·ml-1;the effeciency that simultaneously used two kinds of disinfectants was dissimilar.Terminating or not the disinfectant function did not affect the sterilized effect.Several proposals were suggested to pig raisers about how to use the disinfectants.