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Volume 26 Issue 2
Nov.  2011
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Article Contents
HUA Wen-jun, LIU Xi-mei, CHENG Ni, QIAO Xian-feng, ZHENG Xin-min. Major Infectious Diseases Susceptible to sFat-1 Transgenic Pigs[J]. Fujian Journal of Agricultural Sciences, 2011, 26(2): 180-183.
Citation: HUA Wen-jun, LIU Xi-mei, CHENG Ni, QIAO Xian-feng, ZHENG Xin-min. Major Infectious Diseases Susceptible to sFat-1 Transgenic Pigs[J]. Fujian Journal of Agricultural Sciences, 2011, 26(2): 180-183.

Major Infectious Diseases Susceptible to sFat-1 Transgenic Pigs

  • Received Date: 2010-11-26
  • Rev Recd Date: 2011-01-16
  • Publish Date: 2011-04-15
  • Some major infectious diseases susceptible to the sFat-1 transgenic pigs were closely observed,as it might post an environmental safety threat.Nine infectious diseases were selected for the study on 21 negative(control) and 20 transgenic sFat-1 gene pigs.They included TB,PRRSV,FMDV,CSFV,PRV,SVD,Brucellosis,African swine fever and enterovirus encephalomyelitis.All tests were completed by using ELISA and PCR detection kits.The infection rate of SVD(Swine Vesicular Disease) was 5% in the control group and 20% in the test pigs,indicating a significant susceptibility.There was no significant difference observed for the other 8 infectious diseases.The death rate was 8% in the infected control adult pigs,but 37% among the infected adult pigs in the test group.The liver functions of some sFat-1 gene transgenic pigs were slightly damaged that might have caused their increased susceptibility to SVD.
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  • [1]
    MEISLER M H.Insertional mutation of classical and novel genes in transgenic mice[J].Trends Genetics,1992,8:341-344.
    [2]
    HUA WENJUN,LIU XIMEI,CHENG NI,et al.Determination of physiological biochemical parameters and reproductive performance in transgenic sFat-1 gene pigs[J].Agricultural Science & Technology,2010,11 (5):106-108.
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