Epidemiology and Genetic Variation of Duck Hepatitis A Virus Type 1 Circulating in Some Regions of China

FU Guang-hua; CHEN Cui-teng; WEN Ming-gen; SHI Shao-hua; CHEN Hong-mei; WAN Chun-he; FU Qiu-ling; CHENG Long-fei; LIU Rong-chang; HUANG Yu

doi:10.19303/j.issn.1008-0384.2018.02.001

Volume 33 Issue 2

Mar. 2019

Turn off MathJax

Article Contents

Article Navigation > Fujian Journal of Agricultural Sciences > 2018 > 33(2): 109-113

FU Guang-hua, CHEN Cui-teng, WEN Ming-gen, SHI Shao-hua, CHEN Hong-mei, WAN Chun-he, FU Qiu-ling, CHENG Long-fei, LIU Rong-chang, HUANG Yu. Epidemiology and Genetic Variation of Duck Hepatitis A Virus Type 1 Circulating in Some Regions of China[J]. Fujian Journal of Agricultural Sciences, 2018, 33(2): 109-113. doi: 10.19303/j.issn.1008-0384.2018.02.001

Citation:

FU Guang-hua, CHEN Cui-teng, WEN Ming-gen, SHI Shao-hua, CHEN Hong-mei, WAN Chun-he, FU Qiu-ling, CHENG Long-fei, LIU Rong-chang, HUANG Yu. Epidemiology and Genetic Variation of Duck Hepatitis A Virus Type 1 Circulating in Some Regions of China[J]. Fujian Journal of Agricultural Sciences, 2018, 33(2): 109-113. doi: 10.19303/j.issn.1008-0384.2018.02.001

Citation:

FU Guang-hua, CHEN Cui-teng, WEN Ming-gen, SHI Shao-hua, CHEN Hong-mei, WAN Chun-he, FU Qiu-ling, CHENG Long-fei, LIU Rong-chang, HUANG Yu. Epidemiology and Genetic Variation of Duck Hepatitis A Virus Type 1 Circulating in Some Regions of China[J]. Fujian Journal of Agricultural Sciences, 2018, 33(2): 109-113. doi: 10.19303/j.issn.1008-0384.2018.02.001

PDF( 1412 KB)

Epidemiology and Genetic Variation of Duck Hepatitis A Virus Type 1 Circulating in Some Regions of China

doi: 10.19303/j.issn.1008-0384.2018.02.001

FU Guang-hua^{1, 2},
CHEN Cui-teng^{1, 3},
WEN Ming-gen⁴,
SHI Shao-hua^{1, 2},
CHEN Hong-mei^{1, 2},
WAN Chun-he^{1, 2},
FU Qiu-ling^{1, 2},
CHENG Long-fei^{1, 2},
LIU Rong-chang^{1, 2},
HUANG Yu^{1, 2, 3
,
,}

1.
Institute of Animal Husbandry and Veterinary Medicine, Fujian Academy of Agricultural Sciences, Fuzhou, Fujian 350013, China
2.
Fujian Provincial Key Laboratory for Avian Diseases Control and Prevention, Fuzhou, Fujian 350013, China
3.
Fujian Animal Diseases Control Technology Center, Fuzhou, Fujian 350013, China
4.
Bureau of Animal Husbandry and Veterinary Medicine of Ji'an County of Jiangxi, Ji'an, Jiangxi 343100, China

Received Date: 2017-10-25
Rev Recd Date: 2018-02-03
Publish Date: 2018-02-01

Abstract

Abstract

The epidemic prevalence and molecular variation of duck hepatitis A virus type 1 (DHAV-1) were investigated. Three-hundred-twenty-seven clinical samples collected in 2015-2016 from Fujian and surrounding provinces were used for the virus detection and isolation. Thirty-five of these samples (10.7%)were found to be pusitive for DHAV-1. From the 35 positive specimens, 23 strains were isolated, mainly from shelducks and mule ducks of less than 30-day-old. The sequence analysis on VP1 gene of the 23 isolates showed 93.3%-99.9% homology, and the strains could be divided into 2 subgroups with a genetic distance of 0.06. Among them, 18 isolates clustered in a currently prevalent subgroup which contains the virus (MPZJ1206)causing yellowed-pancreas in ducklings. On the other hand, all 23 isolates shared merely 91.3-96.2% nucleotide sequence homology with the strain used for vaccination abroad and domestically. It appeared that genetic variations existed among the various DHAV-1 strains.
- duck hepatitis A virus type 1,
- VP1 gene,
- variation analysis

FullText(HTML)

References(17)

References

[1]	KNOWLES N J, HOVI T, HYYPIA T, et al. Family Picornaviridae[A]. In Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses, 2012: 855-880.
[2]	SAIF Y M. 禽病学[M]. 苏敬良, 高福, 索勋, 译. 12版. 北京: 中国农业出版社, 2012: 431-443.
[3]	TSENG C H, TSAI H J. Molecular characterization of a new serotype of duck hepatitis virus[J]. Virus Res, 2007, 126(1-2):19-31. doi: 10.1016/j.virusres.2007.01.012
[4]	KIM M C, KWON Y K, JOH S J, et al. Recent Koren isolates of duck hepatitis virus reveal the presence of a new geno-and serotype when compared to duck hepatitis virus type 1 type strain[J]. Arch Virol, 2007, 152(11):2059-2072. doi: 10.1007/s00705-007-1023-0
[5]	WANG L, PAN M, FU Y, et al. Classification of duck hepatitis virus into three genotypes based on molecular evolutionary analysis[J]. Virus Genes, 2008, 37(1):52-59. doi: 10.1007/s11262-008-0233-1
[6]	黄均建.小鸭病毒性肝炎研究[M].上海:上海农业科学院畜牧兽医研究所, 1963.
[7]	郭玉璞, 潘文石.北京病毒性肝炎血清型的初步鉴定[J].中国兽医杂志, 1984, 10(11):2-3. http://cdmd.cnki.com.cn/Article/CDMD-90106-1013279893.htm
[8]	王平, 潘文石, 胡寿文, 等.北京小鸭病毒性肝炎的研究——(一)诊断和防治[J].北京大学学报:自然科学版, 1980, 16(1):57-76. http://www.cnki.com.cn/Article/CJFDTOTAL-BJDZ198001006.htm
[9]	LIU G Q, WANG F, NI Z, et al. Genetic diversity of the VP1 gene of duck hepatitis virus type 1(DHV-1) isolates from southeast China is related to isolate attenuation[J]. Virus Research, 2008, 124(11):1-5. https://es.scribd.com/document/358385920/1119991420-pdf
[10]	FU Y, PAN M, WANG X, et al. Molecular detection and typing of duck hepatitis A virus directly from clinical specimens[J]. Vet Microbiol, 2008, 131(3/4):247-257. http://cn.bing.com/academic/profile?id=161229d691cc8ed741299cc6557dba8a&encoded=0&v=paper_preview&mkt=zh-cn
[11]	林世棠, 黄瑜, 黄纪铨, 等.一种新的鸭传染病研究Ⅰ.流行情况与初步诊断[J].中国预防兽医学报, 1996, 18(4):14-17. http://www.cnki.com.cn/Article/CJFDTotal-ZGXQ201007006.htm
[12]	陈建红, 张济培, 司兴奎, 等.标准鸭肝炎1型血清对鸭肝炎野毒株的免疫保护试验[J].中国兽医学报, 2001, 21(3):231-234. http://www.cnki.com.cn/Article/CJFDTOTAL-ZGXQ199101006.htm
[13]	何冉娅, 于淼, 张玉玲, 等. 2007~2009年华南地区鸭肝炎病毒流行病学调查及分离株的VP1基因变异分析[J].中国动物传染病学报, 2010, 18(1):7-17. http://kns.cnki.net/KCMS/detail/detail.aspx?filename=zsjb201001005&dbname=CJFD&dbcode=CJFQ
[14]	TSENG C H, KNOWLES N J, TSAI H J. Molecular analysis of duck hepatitis virus type 1 indicates that it should be assigned to a new genus[J]. Virus Research, 2007, 123(2):190-203. doi: 10.1016/j.virusres.2006.09.007
[15]	GUERIN J L, ALBARIC O, NOUTARY V, et al. A duck hepatitis virus type I is agent of pancreatitis and encephalitis in Muscovy duckling[C]//Proceedings of the 147th American Veterinary Medicine Association/50th American Association of Avian Pathologists Conference, 14-18 July 2007, Washington, DC, USA, Abs 4585.
[16]	傅光华, 陈红梅, 黄瑜, 等.雏番鸭胰腺型鸭1型甲肝病毒分离鉴定及VP1基因分析[J].福建农业学报, 2012, 27(9):945-950. http://kns.cnki.net/KCMS/detail/detail.aspx?filename=fjnx201209009&dbname=CJFD&dbcode=CJFQ
[17]	KIM M C, KWON Y K, JOH S J, et al. Molecular analysis of duck hepatitis virus type 1 reveal s a novel lineage close to t he genus parechovirus in the family Picornaviridae[J]. J Gen Virol, 2006, 87(11):3307-3316. doi: 10.1099/vir.0.81804-0