Anti-inflammatory and Intestinal Movement Enhancing Effects of Water Extract from Flowers of Eriobotrya japonica (Thunb.) Lindl
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摘要: 研究了贵妃枇杷茶水提取物（WGFT）对干预炎症及对小肠推进功能的影响。结果表明，与正常对照组相比，不同剂量组WGFT均能降低大鼠棉球肉芽肿的干重，其中高剂量组和中剂量组棉球肉芽的干重分别降低39.98%（P<0.01）、40.02%（P<0.01），低剂量组降低31.98%（P<0.05）。高剂量组WGFT和中剂量组WGFT小鼠耳肿胀度与正常对照度相比明显减少，其中高剂量组的小鼠耳肿胀度降低30.55%（P<0.01），中剂量组降低23.47%（P<0.05）。研究还显示高剂量组WGFT和中剂量组WGFT对试验小鼠的肠推进率分别比模型对照组提高了87.19%（P<0.01）、68.87%（P<0.01）。研究证实贵妃枇杷花茶具有显著的干预急性炎症的作用，还能明显促进模型小鼠小肠运动能力，为后续枇杷花的开发利用提供理论支持。Abstract: Anti-inflammatory and small intestinal movement enhancing effects of water extract from the Guifei loquat flower tea (WGFT) were studied. Dosages of the water extractadministered to the lab mice in the experiment included the high (1.6 g·kg-1), medium (0.8 g·kg-1), and low (0.4 g·kg-1) levels. The results showed that all doses of WGFT reduced the formation of granuloma in themice. In comparison with control, the high, medium, and low doses of the teadecreased the granuloma weight in miceby 39.98% (P<0.01), 40.02% (P<0.01), and 31.98% (P<0.05), respectively. For the ear inflammation reductionon mice, the high dose reducedthe ear-swellingby 30.55% (P<0.01), and medium dose by 23.47% (P<0.05) over control. As for the effect on the small intestinal movement, the high and mediumlevels of WGFT improvedthe movement by 87.19% (P<0.01)and 68.87% (P<0.01), respectively, as compared with that of control. It appeared thatthe water extract significantly induced anti-inflammatory and small intestinal movement enhancing effects on the mice. Itsuggested a potential medical application of the loquat flowers in the future.
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Key words:
- guifei loquat /
- flower water extract /
- anti-inflammation /
- small intestinal movement
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图 1 WGFT对大鼠棉球肉芽肿干重的影响
注：**表示 P<0.01，*表示P<0.05。下同。
Figure 1. Effect of loquat flower tea on weight of granuloma
图 2 WGFT对二甲苯致小鼠耳肿胀度的影响
Figure 2. Effect of loquat flower tea on ear-swelling induced byxylene on mice
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