The Identity and Clinic Infectious Symptoms of the New Genotype Muscovy Duck Parvovirus
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摘要: 2008年下半年以来,福建省、浙江省、安徽省及江苏省等地部分鸭场或养鸭户的雏半番鸭和台湾白鸭出现低病死率,约于40日龄起脚易断、上喙变短占近30%,至出栏时残次鸭达60%;免疫接种了雏番鸭细小病毒弱毒活疫苗的雏番鸭依然发生类雏番鸭“三周病”,除出现死亡外,幸存鸭的番鸭翅脚易断、上喙变短,83%感染鸭成为僵鸭,对我国养鸭业造成了较大的直接经济损失。经病原学检测、病毒分离鉴定和实验室感染试验,发现其病原为与原经典的雏番鸭细小病毒(MDPV)在基因组上、感染宿主范围和致病性存在较大差异的番鸭细小病毒,鉴于此,将之暂定名为新型番鸭细小病毒(NMDPV)。Abstract: There were some Mule Muscovy ducks and the Taiwan White ducks,which was located in Fujian,Zhejiang,Anhui and Jiangsu Province in China,had the clinic symptoms with weak feet and low mortality rate since the second half of 2008.After the age of 40-day,the ducks were easily fracture,with nearly 30 percentage having the short beak infectious symptoms.About 60 percentage ducks had not reach the slaughter standards.The Muscovy ducklings immunized with the MDPV live actuated vaccine also had such infectious symptoms,typically like the MDPV infectious symptoms,causing greatly economic loss to the ducks farming industry.After the detection of new pathogen,virus isolation and the challenge experiments in Muscovy ducklings,we discovered that the new virus had many differences with the typical Muscovy duck parvovirus such as the genome,the host range and the pathogenicity.In conclusion,we suggested the newly infectious diseases named with new genotype Muscovy duck parvovirus,to avoid Muscovy duck origin parvovirus definition confusion.
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