Abstract: Taking an instance of soil and water erosion for case study on the optimization layout of plantation land, the layout of flue-cured tobacco plantation in Changting was optimized based on the principle in“suitability, localization and intensives”with integration of GIS and mathematical modeling.The results showed that, account of total cropland in Changting, the area suited for flue-cured tobacco plantation was 80.08%, and 79.74% of which was high or moderate suitability.Among total flue-cured tobacco plantation land, the optimal localization in suitability showed that the first and secondary suitable planting area was for 92.82% in total optimized arrangement.The towns including Datong, Hetian, Tongfang, Xinqiao and Zhoutian could be planning as key developing area, and those including Cewu, Gucheng, Guanqian and Tufang could be planning as reserve area for flue-cured tobacco industry in Changting.